Tariq Castro-Fields intercepted Shea Patterson's screen pass midway through the second quarter and Clifford arced his second touchdown pass to Hamler five plays later to make it 21-0.
Michigan State is heading into its first home game in a month and will do so as an underdog.
A second look shows that Bell had the ball in his hands and just couldn't keep it there.
Penn State linebacker Micah Parsons was everywhere in this game, battling through double and triple teams to lead the team with 14 tackles. The snafu was a major boon to the Nittany Lions, who were reeling throughout the fourth quarter.
But when Penn State went up 21-0 in the second quarter - MI scored a touchdown before halftime - fans were angry. Well, Michigan didn't have the right defense on the field, he says.
Best kick: Blake Gillikin boomed a 60-yard punt that was covered well by Dan Chisena in the third quarter. The Wolverines punted the ball back seven plays later.
Most telling statistic: Penn State was outgained 417-283 and, after building a 21-0 lead, punted six times in the second half. Hamler's 100-yard kickoff return to start the second half was wiped out by two holding penalties against Penn State. But Michigan wideout Ronnie Bell dropped a potential tying touchdown with Penn State safety Lamont Wade playing tight coverage. The Nittany Lions and Buckeyes are the only undefeated teams in the division and won't play until the next-to-last game of the regular season.
"They hit us on a long one in the first half, inside fade route, and they had a good call on there", head coach Jim Harbaugh explained.
WORST DECISION Penn State simply could not get out of its offensive rut after taking a 21-0 lead, frequently running on first and second down to set up third-and-longs that it couldn't convert.
Best run: Facing third-and-3 from the Lions' own 10 with 1:51 remaining and MI having burned two of its three timeouts, Hamler - despite being the smallest player on the field at 175 pounds - slammed forward for 4 yards and the first down that clinched the game. Appearing to be completely confused by Michigan's pre-snap shifts on the defensive side of the ball, the Nittany Lions only recovered momentarily in pulling off a 53-yard touchdown pass to Hamler. The most electric player on the field Saturday night, Hamler was the difference in the Nittany Lions' win.