Jesus is now expected to deputise up front over the coming games starting against Donetsk on Tuesday night where City need just a point to qualify from Group C and book their place in the knockout stages of the Champions League. This highlight from the London Stadium saw Tottenham hold off a West Ham fightback as Jose Mourinho took all 3 points for Tottenham vs West Ham in the Premier League. "My teams, always we try but I accept that the others can better".
A limping Aguero was replaced by Gabriel Jesus in Saturday's 2-1 win over Chelsea and Guardiola said they would need a "miracle" if the Argentine was to be fit for the Premier League match against rivals Manchester United on December 7.
That win was their 12th in 13 Premier League games this season and the Reds are now the heavy favourites to win the title following their brilliant start.
Sadio Mane opened the scoring shortly after half-time, which was perhaps unsurprising given his superb record against the Eagles.
Jesus has been restricted to just four Premier League starts this term, but is likely to be drafted in for Aguero while he recovers from his tendon issue.
Indeed, Liverpool FC have only dropped two points so far this season in what has been a sensational start to the new campaign for Klopp's men.
Roberto Firmino had the final say, though, prodding home after a corner had caused chaos in the Palace penalty area.
Having lost his first ever competitive game as manager, with Benfica in September 2000, Mourinho has gone unbeaten in his first game in charge at each of his eight clubs since then.
The Brazil forward insists he is ready to fill the void left in Guardiola's line up by a key performer, with it his desire to keep improving and stake a claim for a more permanent spot in the City team.
Both sides are still in the Champions League and will go through to the last 16.
N'Golo Kante gave Chelsea a 21st-minute lead but, remarkably, Lampard's side did not manage another shot on target for the remainder of the match.
Talking about the match, riding on goals from Kevin du Bruyne and Riyad Mahrez, City defeated guests Chelsea 2-1. The last time two teenagers scored in a Premier League game for United was in October 2005, when Wayne Rooney and Giuseppe Rossi netted against Sunderland.