Four of the six already had health conditions, which may have made them more prone to complications from the flu.
Flu-like symptoms include: fever, cough, chills, a runny or stuffy nose, sore throat and headaches.
The first influenza-related adult death (over 65 years of age) was reported last week in Douglas County.
Locally, there are thousands of flu-related hospitalizations and an estimated 70 to 500 deaths from flu in King County every year.
In the week December 15-21, a total of 100,442 people sought outpatient and emergency treatment for flu-like symptoms at hospitals and clinics around the country, an increase of 7.6 percent from the previous week, according to CDC numbers.
The best protection is to take the flu vaccine, the CDC stressed.
Avoid people who appear sick.
Influenza A and influenza B cause the same type of illness.
The flu season is continuing to hit southern states hard as influenza begins to spread across the country.
Someone who gets the flu after getting a flu shot is still less contagious and should experience fewer symptoms for a shorter period of time. Eighty percent of these deaths occurred in unvaccinated children.
Denver Health has dealt with 197 of the reported cases in Colorado.
"You are far more likely to be exposed to the flu in the next two months than you were during the past two months", he said.
Even after being vaccinated, the state Health Department recommends washing hands with soapy water or using alcohol-based hand sanitizers and covering coughs and sneezes with a sleeve or tissue to help prevent the spread of illness.
The health department and Dr.McPherson say flu shots are key, and it's not too late to get one this season. Manny Alvarez sits down with a Harvard Medical School doctor to discuss everything you need to know about this year's flu season. "Vaccination is safe, effective, and widely available at pharmacies, community health clinics, and most healthcare provider offices".